Letrozole vs Clomid for PCOS: Which Works Better for Ovulation?
For most women with PCOS who are not ovulating, letrozole is now the preferred first-line tablet over clomiphene (Clomid). In a large trial and in the 2023 international PCOS guideline, letrozole gave higher ovulation and live birth rates, with fewer twins and less thinning of the uterine lining. The right choice still depends on your individual assessment.